“CARMELO & LA LA ANTHONY SEPERATION”

The Knick superstar’s wife reportedly moved out of their home in part due to the stress of his failed season — a decision that comes as Melo’s boss said No. 7 should play “somewhere else.”

While the couple has had problems in the past, suffering through 51 losses apparently placed a heavy strain on the nearly seven-year marriage for La La Anthony, sources told TMZ.

The breakup is reportedly amicable, with Anthony and La La agreeing to keep their only child in New York for the foreseeable future, the site reported.

Anthony, 32, also is on the verge of an ugly split with the team he’s called home for the last seven seasons — a divorce that seemed even more likely after Jackson, the Knicks president, said Melo should go at a season-ending press conference Friday.

“I think the direction with our team is that he is a player that would be better off somewhere else and using his talents somewhere he can win, or chase that championship,” Jackson said.

But leaving would be too much for La La, 37, to bear, sources told The Post.

“Especially if he isn’t going to be in NYC, why would she want to be traipsing around to a city like Cleveland so he can go win a ring?” a source explained.

Sources said the couple lost their spark when Anthony got traded to the Knicks from Denver in 2011.